WWOX Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for WWOX Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2735647)
Target
See all WWOX ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This WWOX protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human WWOX / FOR (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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WW Domain Containing Oxidoreductase (WWOX) (AA 1-414) protein (His tag)
custom-made WWOX Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
WW Domain Containing Oxidoreductase (WWOX) (AA 1-414) protein (GST tag)WWOX Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
WW Domain Containing Oxidoreductase (WWOX) (AA 1-234) protein (His tag)WWOX Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- WWOX (WW Domain Containing Oxidoreductase (WWOX))
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Alternative Name
- Wwox,for
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Background
- This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 46.5 kDa
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NCBI Accession
- NP_057457
Target
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