WWOX Protein (AA 1-234) (His tag)
Quick Overview for WWOX Protein (AA 1-234) (His tag) (ABIN7278826)
Target
See all WWOX ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-234
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Purification tag / Conjugate
- This WWOX protein is labelled with His tag.
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Sequence
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MAALRYAGLD DTDSEDELPP GWEERTTKDG WVYYANHTEE KTQWEHPKTG KRKRVAGDLP YGWEQETDEN GQVFFVDHIN KRTTYLDPRL AFTVDDNPTK PTTRQRYDGS TTAMEILQGR DFTGKVVVVT GANSGIGFET AKSFALHGAH VILACRNMAR ASEAVSRILE EWQQGAATTV YCAAVPELEG LGGMYFNNCC RCMPSPEAQS EETARTLWAL SERLIQERLG SQSG -
Characteristics
- WWOX, 1-234 aa, Human, His-tagged, Recombinant, E.coli
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Purification
- > 85% by SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- WWOX (WW Domain Containing Oxidoreductase (WWOX))
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Alternative Name
- WWOX
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Background
- WWOX, also known as WW domain containing oxidoreductase, is a proapoptotic protein and a tumor suppressor protein. WWOX is found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This protein may function synergistically with TP53/p53 to control genotoxic stress-induced cell death. It also plays a role in tumor necrosis factor (TNF) -mediated cell death. Recombinant human WWOX protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
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Molecular Weight
- 28.3 kDa (254aa) confirmed by MALDI-TOF
Target
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