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WWOX Protein (AA 1-234) (His tag)

Recombinant WWOX protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7278826
$792.31
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Quick Overview for WWOX Protein (AA 1-234) (His tag) (ABIN7278826)

Target

See all WWOX Proteins
WWOX (WW Domain Containing Oxidoreductase (WWOX))

Protein Type

Recombinant

Origin

  • 5
  • 1
  • 1
  • 1
Human

Source

  • 3
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 85 %
  • Protein Characteristics

    AA 1-234

    Purification tag / Conjugate

    This WWOX protein is labelled with His tag.

    Sequence

    MAALRYAGLD DTDSEDELPP GWEERTTKDG WVYYANHTEE KTQWEHPKTG KRKRVAGDLP YGWEQETDEN GQVFFVDHIN KRTTYLDPRL AFTVDDNPTK PTTRQRYDGS TTAMEILQGR DFTGKVVVVT GANSGIGFET AKSFALHGAH VILACRNMAR ASEAVSRILE EWQQGAATTV YCAAVPELEG LGGMYFNNCC RCMPSPEAQS EETARTLWAL SERLIQERLG SQSG

    Characteristics

    WWOX, 1-234 aa, Human, His-tagged, Recombinant, E.coli

    Purification

    > 85% by SDS-PAGE
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • Target

    WWOX (WW Domain Containing Oxidoreductase (WWOX))

    Alternative Name

    WWOX

    Background

    WWOX, also known as WW domain containing oxidoreductase, is a proapoptotic protein and a tumor suppressor protein. WWOX is found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This protein may function synergistically with TP53/p53 to control genotoxic stress-induced cell death. It also plays a role in tumor necrosis factor (TNF) -mediated cell death. Recombinant human WWOX protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

    Molecular Weight

    28.3 kDa (254aa) confirmed by MALDI-TOF
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