ZIC2 Protein (ZIC2) (Myc-DYKDDDDK Tag)
ZIC2
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
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- Target See all ZIC2 Proteins
- ZIC2
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ZIC2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ZIC2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ZIC2 Protein
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ZIC2 (ZIC2) (AA 1-532) protein (Strep Tag)
Crystallography grade ZIC2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ZIC2
- Alternative Name
- Zic2 (ZIC2 Products)
- Synonyms
- HPE5 Protein, Ku Protein, cb851 Protein, fb26a03 Protein, wu:fb26a03 Protein, zic2 Protein, zic2.1 Protein, hpe5 Protein, hm:zeh0655 Protein, id:ibd5017 Protein, zic2.2 Protein, zic2l Protein, Zic family member 2 Protein, zinc finger protein of the cerebellum 2 Protein, zic family member 2 (odd-paired homolog, Drosophila), a Protein, Zic family member 2 L homeolog Protein, zic family member 2 (odd-paired homolog, Drosophila) b Protein, ZIC2 Protein, Zic2 Protein, zic2a Protein, zic2.L Protein, zic2b Protein
- Background
- Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets. Its transcriptional activity is repressed by MDFIC. Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline. Drives the expression of EPHB1 on ipsilaterally projecting growth cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 54.8 kDa
- NCBI Accession
- NP_009060
- Pathways
- Tube Formation
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