ZNF346 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2736004

This Recombinant ZNF346 protein is expressed in HEK-293 Cells.

Quick Overview for ZNF346 Protein (Myc-DYKDDDDK Tag) (ABIN2736004)

Target: ZNF346 (Zinc Finger Protein 346 (ZNF346))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This ZNF346 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human ZNF346 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ZNF346 (Zinc Finger Protein 346 (ZNF346))

Alternative Name: Znf346

Background: The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight: 32.8 kDa

NCBI Accession: NP_036411