DLL1 Protein (AA 18-545) (Fc Tag)
Quick Overview for DLL1 Protein (AA 18-545) (Fc Tag) (ABIN2745651)
Target
See all DLL1 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
-
-
Protein Characteristics
- AA 18-545
-
Purification tag / Conjugate
- This DLL1 protein is labelled with Fc Tag.
-
Purpose
- DLL1 (human):Fc (human) (rec.)
-
Specificity
- Interacts with human Notch1 (as confirmed by flow cytometry).
-
Cross-Reactivity
- Human
-
Characteristics
- Human DLL1 extracellular domain (aa 18-545) is fused at the C-terminus to the Fc portion of human IgG1.
-
Endotoxin Level
- <0.01EU/μg purified protein (LAL test).
-
Biological Activity Comment
- Inhibits adipogenesis of 3T3L-1 cells. Induces the Notch target gene HES-1 when coated on a plate at 1μg/ml.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
delta-Like 1 (DLL1) protein (Fc Tag)
DLL1 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
delta-Like 1 (DLL1) (Active) protein (His tag)DLL1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Reconstitute in distilled water.
-
Concentration
- Lot specific
-
Buffer
- Contains PBS.
-
Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
-
Expiry Date
- 6 months
-
-
- DLL1 (delta-Like 1 (DLL1))
-
Alternative Name
- DLL1
-
Background
-
Delta-like Protein 1, Delta1
DLL1 (Delta-like protein, Delta1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.
-
Molecular Weight
- ~100kDa (SDS-PAGE)
-
UniProt
- O00548
-
Pathways
- Notch Signaling, Stem Cell Maintenance
Target
-
