PARP2 Protein (His tag)
Quick Overview for PARP2 Protein (His tag) (ABIN2745795)
Target
See all PARP2 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This PARP2 protein is labelled with His tag.
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Purpose
- PARP-2 [ARTD2] (mouse) (rec.) (His) (high purity)
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Cross-Reactivity
- Mouse
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Characteristics
- Mouse full-length PARP-2 [ARTD2] is fused to a His-tag.
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Biological Activity Comment
- >600U/mg protein.
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Poly (ADP-Ribose) Polymerase 2 (PARP2) (AA 435-534) protein (GST tag)
PARP2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Poly (ADP-Ribose) Polymerase 2 (PARP2) (AA 430-583) protein (His-IF2DI Tag)PARP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- In 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride and 50 mM imidazole, 0.2 % NP-40 and 10 % glycerol.
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Handling Advice
- After opening, prepare aliquots and store at -80 °C. Avoid freeze/thaw cycles.
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Storage
- -20 °C,-80 °C
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Storage Comment
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Short Term Storage: -20°C
Long Term Storage: -80°C
Use & Stability: Stable for at least 6 months after receipt when stored at -80°C.
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Expiry Date
- 6 months
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- PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
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Alternative Name
- PARP-2 [ARTD2]
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Background
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Poly(ADP-ribose) Polymerase, ADP-ribosyltransferase Diphtheria Toxin-like 2, NAD(+) ADP-ribosyltransferase 2
PARP-2 [ARTD2] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
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UniProt
- O88554
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Pathways
- DNA Damage Repair
Target
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