PLGF Protein
Quick Overview for PLGF Protein (ABIN2745802)
Target
See all PLGF (PGF) ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Purpose
- PLGF (human) (rec.)
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Cross-Reactivity
- Human
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Characteristics
- Human PLGF (131aa).
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Biological Activity Comment
- Measured by its ability to bind to immobilized rhsFlt-1 in a functional ELISA. Recombinant human PLGF can bind to immobilized rhsFlt-1 (100ng/well) with a linear range at 0.5-10ng/ml.
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Placenta Growth Factor (PGF) (AA 19-221) protein (Fc Tag)
PGF Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Placenta Growth Factor (PGF) (Active) proteinPGF Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Placenta Growth Factor (PGF) (AA 19-158) protein (His tag)PGF Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Placenta Growth Factor (PGF) (AA 19-158) protein (Fc Tag)PGF Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Placenta Growth Factor (PGF) (AA 19-170) protein (Fc Tag)PGF Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Placenta Growth Factor (PGF) (AA 19-170) (Active) protein (His tag)PGF Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Placenta Growth Factor (PGF) (AA 19-221) (Active) protein (Fc Tag)PGF Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Placenta Growth Factor (PGF) protein (His tag)PGF Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Placenta Growth Factor (PGF) (Active) protein (His tag)PGF Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
Placenta Growth Factor (PGF) (AA 1-170) protein (His-IF2DI Tag)PGF Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with 50 mM acetic acid or PBS/water. This solution can be diluted into other buffered solutions or stored frozen for future use.
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Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.
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Expiry Date
- 6 months
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- PLGF (PGF) (Placenta Growth Factor (PGF))
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Alternative Name
- PLGF
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Background
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Placenta Growth Factor, PLGF-1, PLGF-131
Human placenta growth factor-1 (PLGF-1, PLGF) binds to the receptor FLT1/VEGFR-1. It acts as a potent chemoattractant for monocytes and only as a very weak mitogen for some endothelial cell types. The physiological function in vivo is still controversial. In several reports it was shown not to be a potent mitogen for endothelial cells and not angiogenic in vivo by using different assays. It was shown that PLGF from cell culture supernatants was angiogenic in the CAM assay and in the rabbit cornea assay.
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Molecular Weight
- ~34kDa (dimer)
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UniProt
- P49763
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Pathways
- VEGFR1 Specific Signals
Target
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