PLGF Protein
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- Target See all PLGF (PGF) Proteins
- PLGF (PGF) (Placenta Growth Factor (PGF))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Insect cells (Sf9)
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human PLGF (131aa).
- Purity
- >95 % (SDS-PAGE)
- Top Product
- Discover our top product PGF Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Measured by its ability to bind to immobilized rhsFlt-1 in a functional ELISA. Recombinant human PLGF can bind to immobilized rhsFlt-1 (100ng/well) with a linear range at 0.5-10ng/ml.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 50 mM acetic acid or PBS/water. This solution can be diluted into other buffered solutions or stored frozen for future use.
- Concentration
- Lot specific
- Buffer
- Lyophilized.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- PLGF (PGF) (Placenta Growth Factor (PGF))
- Alternative Name
- PLGF (PGF Products)
- Synonyms
- D12S1900 Protein, PGFL Protein, PLGF Protein, PlGF-2 Protein, SHGC-10760 Protein, AI854365 Protein, PIGF Protein, Plgf Protein, PlGF Protein, placental growth factor Protein, placenta growth factor Protein, PGF Protein, Pgf Protein, PLGF Protein
- Background
- Human placenta growth factor-1 (PLGF-1, PLGF) binds to the receptor FLT1/VEGFR-1. It acts as a potent chemoattractant for monocytes and only as a very weak mitogen for some endothelial cell types. The physiological function in vivo is still controversial. In several reports it was shown not to be a potent mitogen for endothelial cells and not angiogenic in vivo by using different assays. It was shown that PLGF from cell culture supernatants was angiogenic in the CAM assay and in the rabbit cornea assay.
- Molecular Weight
- ~34kDa (dimer)
- UniProt
- P49763
- Pathways
- VEGFR1 Specific Signals
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