KAT5 Protein (His tag)
Quick Overview for KAT5 Protein (His tag) (ABIN2745869)
Target
See all KAT5 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
-
-
Purification tag / Conjugate
- This KAT5 protein is labelled with His tag.
-
Purpose
- TIP60 (human) (rec.) (His) (highly active)
-
Cross-Reactivity
- Human
-
Characteristics
- Human TIP60 is fused to a His-tag.
-
Biological Activity Comment
- 100-200ng are required for standard HAT assay.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!ProductExpression SystemConjugateOriginPrice starts atExpression System Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin HumanPrice starts at $18,117.43Your project requires further customization? Contact us and discover our custom protein solutions
-
K(lysine) Acetyltransferase 5 (KAT5) (AA 1-461) protein (GST tag)
KAT5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
K(lysine) Acetyltransferase 5 (KAT5) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)KAT5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
K(lysine) Acetyltransferase 5 (KAT5) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)KAT5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
K(lysine) Acetyltransferase 5 (KAT5) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)KAT5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
K(lysine) Acetyltransferase 5 (KAT5) (AA 3-513), (partial) protein (His tag)KAT5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- In 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride, 0.2 % NP-40, 50 mM imidazole and 10 % glycerol.
-
Handling Advice
- After opening, prepare aliquots and store at -80 °C. Avoid freeze/thaw cycles.
-
Storage
- -20 °C,-80 °C
-
Storage Comment
-
Short Term Storage: -20°C
Long Term Storage: -80°C
Use & Stability: Stable for at least 6 months after receipt when stored at -80°C.
-
Expiry Date
- 6 months
-
-
- KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
-
Alternative Name
- TIP60
-
Background
-
Histone Acetyltransferase HTATIP, Histone Acetyltransferase KAT5, Lysine Acetyltransferase 5, 60 kDa Tat-interactive Protein
TIP60 is the catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex is required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. TIP60 directly acetylates and activates ataxia-telangiectasia mutated (ATM). In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.
-
UniProt
- Q92993
-
Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Target
-
