TGFA Protein (AA 40-89)
Quick Overview for TGFA Protein (AA 40-89) (ABIN2829976)
Target
See all TGFA ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- AA 40-89
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Sequence
- Val40-Ala89, Accession # P01135
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Characteristics
- Biological Activity: The ED50, as determined by a cell proliferation assay using murine Balb/3T3 cells, is less than 0.4 ng/mL.
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Sterility
- 0.2 μm filtered
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Transforming Growth Factor, alpha (TGFA) (AA 40-89) protein (Fc Tag)
TGFA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transforming Growth Factor, alpha (TGFA) (AA 39-88) protein (Fc Tag)TGFA Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transforming Growth Factor, alpha (TGFA) (AA 40-89) protein (His tag)TGFA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Transforming Growth Factor, alpha (TGFA) (AA 1-159) protein (GST tag)TGFA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 30 % acetonitrile and 0.1 % TFA
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Storage
- -20 °C
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- TGFA (Transforming Growth Factor, alpha (TGFA))
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Alternative Name
- TGFA
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Background
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Relevance: TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
Synonyms: TGF-alpha, ETGF, TGF type 1,], -
Molecular Weight
- 6 kDa
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UniProt
- P01135
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Pathways
- NF-kappaB Signaling, RTK Signaling, EGFR Signaling Pathway
Target
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