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CCL3 Protein

Recombinant CCL3 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN2830201

Quick Overview for CCL3 Protein (ABIN2830201)

Target

See all CCL3 Proteins
CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 18
  • 8
  • 6
  • 3
  • 1
  • 1
  • 1
Rat

Source

  • 26
  • 4
  • 3
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Application

Functional Studies (Func)

Purity

>98 % as determined by SDS-PAGE and HPLC.
  • Sequence

    APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA

    Characteristics

    Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemoattract bioassay using human blood monocytes is in a concentration range of 10-100 ng/mL.

    Sterility

    0.2 μm filtered
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C
  • Target

    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

    Alternative Name

    Ccl3

    Background

    Relevance: Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin.
    Synonyms: Macrophage inflammatory protein 1-alpha, Small-inducible cytokine A3

    Molecular Weight

    7.9 kDa

    UniProt

    P50229

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Autophagy
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