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Cardiotrophin 1 Protein (CTF1)

Recombinant Cardiotrophin 1 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN2830420

Quick Overview for Cardiotrophin 1 Protein (CTF1) (ABIN2830420)

Target

See all Cardiotrophin 1 (CTF1) Proteins
Cardiotrophin 1 (CTF1)

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 8
  • 4
  • 2
  • 1
Rat

Source

  • 10
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Application

Functional Studies (Func)

Purity

>95 % as determined by SDS-PAGE and HPLC.
  • Sequence

    MSQREGSLED HQTDSSFSFL PHLEAKIRQT HNLARLLTKY ADQLLEEYVQ QQGEPFGLPG FSPPRLPLAG LSGPAPSHAG LPVSERLRQD AAALSALPAL LDAVRRRQAE LNPRAPRLLR SLEDAARQVR ALGAAVETVL AALGAAARGP VPEPVATSAL FTSNSAAGVF SAKVLGLHVC GLYGEWVSRT EGDLGQLVPG GVA

    Characteristics

    Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.5 ng/mL, corresponding to a specific activity of > 2.0 x 106 IU/mg.

    Sterility

    0.2 μm filtered
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    20 mM PB, pH 7.4, 150 mM NaCl

    Storage

    -20 °C
  • Target

    Cardiotrophin 1 (CTF1)

    Alternative Name

    Ctf1

    Background

    Relevance: Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
    Synonyms: CT-1,

    Molecular Weight

    21.4 kDa

    UniProt

    Q63086

    Pathways

    JAK-STAT Signaling
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