Cardiotrophin 1 Protein (CTF1)
Quick Overview for Cardiotrophin 1 Protein (CTF1) (ABIN2830420)
Target
See all Cardiotrophin 1 (CTF1) ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Sequence
- MSQREGSLED HQTDSSFSFL PHLEAKIRQT HNLARLLTKY ADQLLEEYVQ QQGEPFGLPG FSPPRLPLAG LSGPAPSHAG LPVSERLRQD AAALSALPAL LDAVRRRQAE LNPRAPRLLR SLEDAARQVR ALGAAVETVL AALGAAARGP VPEPVATSAL FTSNSAAGVF SAKVLGLHVC GLYGEWVSRT EGDLGQLVPG GVA
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Characteristics
- Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.5 ng/mL, corresponding to a specific activity of > 2.0 x 106 IU/mg.
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Sterility
- 0.2 μm filtered
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 20 mM PB, pH 7.4, 150 mM NaCl
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Storage
- -20 °C
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- Cardiotrophin 1 (CTF1)
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Alternative Name
- Ctf1
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Background
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Relevance: Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
Synonyms: CT-1, -
Molecular Weight
- 21.4 kDa
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UniProt
- Q63086
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Pathways
- JAK-STAT Signaling
Target
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