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Cardiotrophin 1 Protein (CTF1)

CTF1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935297
  • Target See all Cardiotrophin 1 (CTF1) Proteins
    Cardiotrophin 1 (CTF1)
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 9
    • 3
    • 3
    • 1
    Mouse
    Source
    • 11
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    SQREGSLEDH QTDSSISFLP HLEAKIRQTH NLARLLTKYA EQLLEEYVQQ QGEPFGLPGF SPPRLPLAGL SGPAPSHAGL PVSERLRQDA AALSVLPALL DAVRRRQAEL NPRAPRLLRS LEDAARQVRA LGAAVETVLA ALGAAARGPG PEPVTVATLF TANSTAGIFS AKVLGFHVCG LYGEWVSRTE GDLGQLVPGG VA
    Characteristics
    Purified recombinant Mouse Cardiotrophin 1 protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent proliferation of TF-1 cells was 1 x 10^6units/mg.
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product CTF1 Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    Cardiotrophin 1 (CTF1)
    Alternative Name
    Cardiotrophin 1 (CTF1 Products)
    Synonyms
    CTF1 Protein, ct1 Protein, ct-1 Protein, ctf2 Protein, CT-1 Protein, CT1 Protein, cardiotrophin 1 Protein, cardiotrophin-1 Protein, CTF1 Protein, ctf1 Protein, Ctf1 Protein, LOC100736818 Protein
    Background
    CT-1 is a member of the IL6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL11, IL6 and possibly NNT-1/ BCSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations.
    Alternative Names: Cardiotrophin-1, Cardiotrophin 1 protein, Cardiotrophin-1 protein, CT-1 protein, Cardiotrophin-1 protein, Cardiotrophin 1, Cardiotrophin 1
    Molecular Weight
    21.3 kDa
    Pathways
    JAK-STAT Signaling
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