IL1A Protein

Catalog No. ABIN2830807

This Recombinant IL1A protein is produced in Escherichia coli (E. coli).

Quick Overview for IL1A Protein (ABIN2830807)

Target: IL1A (Interleukin 1 alpha (IL1A))

Protein Type: Recombinant

Biological Activity: Active

Origin: Rhesus Monkey

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func)

Purity: >97 % as determined by SDS-PAGE and HPLC.

Product Details

Sequence: SAPFSFLSNM TYHFIRIIKH EFILNDTLNQ TIIRANDQHL TAAAIHNLDE AVKFDMGAYT SSKDDTKVPV ILRISKTQLY VSAQDEDQPV LLKEMPEINK TITGSETNFL FFWETHGTKN YFISVAHPNL FIATKHDNWV CLAKGLPSIT DFQILENQA

Characteristics: Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 10 pg/mL, corresponding to a specific activity of ＞ 1.0 x 108 IU/mg.

Sterility: 0.2 μm filtered

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: IL1A (Interleukin 1 alpha (IL1A))

Alternative Name: IL1A

Background: Relevance: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Synonyms: IL-1 alpha,

Molecular Weight: 18.1 kDa

UniProt: P48089

Pathways: NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints