IL16 Protein
Quick Overview for IL16 Protein (ABIN2830868)
Target
See all IL16 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Sequence
- SAASASAASD ISVESKEATV CTVTLEKTSA GLGFSLEGGK GSLHGDKPLT INRIFKGTEQ GEMVQPGDEI LQLAGTAVQG LTRFEAWNVI KALPDGPVTI VIRRTSLQCK QTTASADS
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Characteristics
- Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral T lymphocytes is in a concentration range of 1.0-100 ng/mL.
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Sterility
- 0.2 μm filtered
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Interleukin 16 (IL16) (AA 1-1322) protein (His tag)
custom-made IL16 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin 16 (IL16) (AA 1-1332) protein (His tag)custom-made IL16 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin 16 (IL16) (AA 1203-1332) (Active) protein (His tag)IL16 Origin: Human Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
Interleukin 16 (IL16) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Interleukin 16 (IL16) (AA 1-454) protein (GST tag)IL16 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 16 (IL16) (AA 502-631) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
Interleukin 16 (IL16) proteinIL16 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 16 (IL16) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 16 (IL16) proteinIL16 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 16 (IL16) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- IL16 (Interleukin 16 (IL16))
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Alternative Name
- Il16
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Background
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Relevance: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4., Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane., Isoform 2 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
Synonyms: IL-16, LCF,] -
Molecular Weight
- 12.2 kDa
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UniProt
- O54824
Target
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