Vaccinia Virus B18R (VACV B18R) (AA 20-351) (Active) protein (His tag)

Catalog No. ABIN2870854

Recombinant Vaccinia Virus B18R protein expressed in HEK-293 Cells.

Quick Overview for Vaccinia Virus B18R (VACV B18R) (AA 20-351) (Active) protein (His tag) (ABIN2870854)

Target: Vaccinia Virus B18R (VACV B18R)

Protein Type: Recombinant

Biological Activity: Active

Origin: Vaccinia Virus (VACV)

Source: HEK-293 Cells

Purity: >95 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 20-351

Purification tag / Conjugate: His tag

Sequence: AA 20-351

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 40.3 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Target Details

Target: Vaccinia Virus B18R (VACV B18R)

Alternative Name: B18R

Target Type: Viral Protein

Background: B18R is a type I interferon (IFN)-binding protein and it is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus, which contains two Ig-like C2-type domains and one Ig-like V-type domain. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R counteracts the antiviral effects of host IFN-alpha/beta. Also, B18R acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.

Molecular Weight: 40.3 kDa

UniProt: P25213