INHBB Protein
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- Target See all INHBB Proteins
- INHBB (Inhibin, beta B (INHBB))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Hi-5 Cells
- Application
- Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human Inhibin beta B chain (INHBB) protein expressed in Hi-5 insect cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- ED50 was determined by its ability to inhibit the proliferation of murine MPC-11 cells is less than or equal to 2.0 ng/ml, corresponding to a specific activity of > 5 x 10^5 units/mg.
- Top Product
- Discover our top product INHBB Protein
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Inhibin, beta B (INHBB) (Active) protein (His tag)
INHBB Origin: Human Host: Tobacco (Nicotiana benthamiana) Recombinant > 97 % by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue. WB, CC Active
Inhibin, beta B (INHBB) protein (His tag)INHBB Origin: Human Host: Tobacco (Nicotiana benthamiana) Recombinant > 97 % by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue. WB
Inhibin, beta B (INHBB) (AA 298-407) protein (GST tag)INHBB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Inhibin, beta B (INHBB) (AA 1-407) protein (GST tag)INHBB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Inhibin, beta B (INHBB) (AA 293-407) protein (His tag)Crystallography grade INHBB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Inhibin, beta B (INHBB) (AA 297-411) protein (His tag)Crystallography grade INHBB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- INHBB (Inhibin, beta B (INHBB))
- Alternative Name
- Inhibin beta B chain (INHBB) (INHBB Products)
- Synonyms
- actbb Protein, actbetaB Protein, inhibin Protein, inhibin, beta B Protein, inhibin beta B L homeolog Protein, inhibin beta B subunit Protein, inhibin beta B Protein, inhibin beta-B Protein, inhibin beta B chain Protein, inhbb Protein, inhbb.L Protein, INHBB Protein, Inhbb Protein, LOC100719829 Protein
- Background
- Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 25.6 kDa
- NCBI Accession
- NP_002184
- Pathways
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
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