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IL-9 Protein

This Recombinant IL-9 protein is produced in Insect Cells.
Catalog No. ABIN5505705

Quick Overview for IL-9 Protein (ABIN5505705)

Target

See all IL-9 (IL9) Proteins
IL-9 (IL9) (Interleukin 9 (IL9))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 13
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
Human

Source

  • 12
  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Insect Cells

Application

Functional Studies (Func), Standard (STD), Antibody Production (AbP), Protein Interaction (PI)

Purity

> 90 % , as determined by Coomassie stained SDS-PAGE.
  • Specificity

    Optimal preservation of protein structure, post-translational modifications and functions.

    Characteristics

    • Recombinant human Interleukin-9 / IL9 protein expressed in Insect cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.

    Endotoxin Level

    Less than 0.1 EU per μg of protein as determine by the LAL method

    Biological Activity Comment

    The ED50 is 0.1-0.5 ng/mL
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays

    Restrictions

    For Research Use only
  • Concentration

    > 50 μg/mL

    Buffer

    1 x PBS, pH 7.4

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    IL-9 (IL9) (Interleukin 9 (IL9))

    Alternative Name

    Interleukin-9 / IL9

    Background

    The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.

    Molecular Weight

    14 kDa

    NCBI Accession

    NP_000581

    Pathways

    JAK-STAT Signaling
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