A2BP1 Protein (His tag)
Quick Overview for A2BP1 Protein (His tag) (ABIN5505765)
Target
See all A2BP1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This A2BP1 protein is labelled with His tag.
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Characteristics
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- Recombinant human Purified recombinant protein of Human RNA binding protein, fox-1 homolog (C. elegans) 1 (RBFOX1), transcript variant 6, full length, with N-terminal HIS tag, expressed in E. coli, 50 μg (full length, N-term HIS tag, transcript variant 6) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
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Purification
- Purified
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Ataxin 2-Binding Protein 1 (A2BP1) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)
A2BP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ataxin 2-Binding Protein 1 (A2BP1) proteinA2BP1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the N-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))
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Alternative Name
- RBFOX1
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Background
- The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 42.6 kDa
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NCBI Accession
- NP_001135806
Target
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