CD47 Protein (CD47) (partial) (Fc Tag)

Catalog No. ABIN5608230

This Recombinant CD47 protein is produced in HEK-293 Cells.

Quick Overview for CD47 Protein (CD47) (partial) (Fc Tag) (ABIN5608230)

Target: CD47

Protein Type: Recombinant

Origin: Rhesus Monkey, Cynomolgus

Source: HEK-293 Cells

Application: Western Blotting (WB)

Purity: >95 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: partial

Purification tag / Conjugate: This CD47 protein is labelled with Fc Tag.

Sequence: Gln 4 - Glu 126

Endotoxin Level: Endotoxin level is less than 1.0 EU per ug by the LAL method.

Application Details

Application Notes: This recombinant protein can be used for WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, pH 7.5

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C,-80 °C

Storage Comment: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Target Details

Target: CD47

Alternative Name: CD47

Background: Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

Molecular Weight: 40.5 kDa

UniProt: G7NZR3