HMOX1 Protein (AA 3-288, partial) (His tag)
Quick Overview for HMOX1 Protein (AA 3-288, partial) (His tag) (ABIN5709671)
Target
See all HMOX1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 3-288, partial
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Purification tag / Conjugate
- This HMOX1 protein is labelled with His tag.
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Sequence
- RPQPDSMPQD LSEALKEATK EVHTQAENAE FMRNFQKGQV TRDGFKLVMA SLYHIYVALE EEIERNKESP VFAPVYFPEE LHRKAALEQD LAFWYGPRWQ EVIPYTPAMQ RYVKRLHEVG RTEPELLVAH AYTRYLGDLS GGQVLKKIAQ KALDLPSSGE GLAFFTFPNI ASATKFKQLY RSRMNSLEMT PAVRQRVIEE AKTAFLLNIQ LFEELQELLT HDTKDQSPSR APGLRQRASN KVQDSAPVET PRGKPPLNTR SQAPLLRWVL TLSFLVATVA VGLYAM
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Purification
- SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))
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Alternative Name
- HMOX1
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Background
- He oxygenase cleaves the he ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of he oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free he sensitizes cells to undergo apoptosis.
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Molecular Weight
- 36.6 kDa
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UniProt
- P09601
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Pathways
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
Target
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