NKRF Protein (AA 4-688, partial) (His tag)
Quick Overview for NKRF Protein (AA 4-688, partial) (His tag) (ABIN5710013)
Target
See all NKRF ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- partial, AA 4-688
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Purification tag / Conjugate
- This NKRF protein is labelled with His tag.
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Sequence
- ILQMAEGIDI GEMPSYDLVL SKPSKGQKRH LSTCDGQNPP KKQAGSKFHA RPRFEPVHFV ASSSKDERQE DPYGPQTKEV NEQTHFASMP RDIYQDYTQD SFSIQDGNSQ YCDSSGFILT KDQPVTANMY FDSGNPAPST TSQQANSQST PEPSPSQTFP ESVVAEKQYF IEKLTATIWK NLSNPEMTSG SDKINYTYML TRCIQACKTN PEYIYAPLKE IPPADIPKNK KLLTDGYACE VRCQNIYLTT GYAGSKNGSR DRATELAVKL LQKRIEVRVV RRKFKHTFGE DLVVCQIGMS SYEFPPALKP PEDLVVLGKD ASGQPIFNAS AKHWTNFVIT ENANDAIGIL NNSASFNKMS IEYKYEMMPN RTWRCRVFLQ DHCLAEGYGT KKTSKHAAAD EALKILQKTQ PTYPSVKSSQ CHTGSSPRGS GKKKDIKDLV VYENSSNPVC TLNDTAQFNR MTVEYVYERM TGLRWKCKVI LESEVIAEAV GVKKTVKYEA AGEAVKTLKK TQPTVINNLK KGAVEDVISR NEIQGRSAEE AYKQQIKEDN IGNQLLRKMG WTGGGLGKSG EGIREPISVK EQHKREGLGL DVERVNKIAK RDIEQIIRNY ARSESHTDLT FSRELTNDER KQIHQIAQKY GLKSKSHGVG HDRYLVVGRK RRKEDLLDQL KQEGQVGHYE LVMPQ
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Purification
- SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- NKRF (NFKB Repressing Factor (NKRF))
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Alternative Name
- NKRF
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Background
- Interacts with a specific negative regulatory elent (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.
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Molecular Weight
- 81.2 kDa
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UniProt
- O15226
Target
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