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SOX2 Protein (AA 1-317, full length) (His-SUMO Tag)

This Recombinant SOX2 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN5710406
$488.40
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Quick Overview for SOX2 Protein (AA 1-317, full length) (His-SUMO Tag) (ABIN5710406)

Target

See all SOX2 Proteins
SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Protein Type

Recombinant

Origin

  • 12
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 7
  • 4
  • 3
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 %
  • Protein Characteristics

    full length, AA 1-317

    Purification tag / Conjugate

    This SOX2 protein is labelled with His-SUMO Tag.

    Sequence

    MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY DVSALQYNSM TSSQTYMNGS PTYSMSYSQQ GTPGMALGSM GSVVKSEASS SPPVVTSSSH SRAPCQAGDL RDMISMYLPG AEVPEPAAPS RLHMSQHYQS GPVPGTAING TLPLSHM

    Purification

    SDS-PAGE
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1-2 mg/mL

    Buffer

    20 mM Tris-HCl based buffer, pH 8.0

    Storage

    -80 °C,4 °C,-20 °C

    Storage Comment

    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target

    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

    Alternative Name

    SOX2

    Background

    Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in bryonic development such as YES1, FGF4, UTF1 and ZFP206 . Critical for early bryogenesis and for bryonic st cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural st cell self-renewal . Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation .

    Molecular Weight

    50.3 kDa

    UniProt

    P48431

    Pathways

    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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