SOX2 Protein (AA 1-317, full length) (His-SUMO Tag)
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- Target See all SOX2 Proteins
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-317
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SOX2 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY DVSALQYNSM TSSQTYMNGS PTYSMSYSQQ GTPGMALGSM GSVVKSEASS SPPVVTSSSH SRAPCQAGDL RDMISMYLPG AEVPEPAAPS RLHMSQHYQS GPVPGTAING TLPLSHM
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product SOX2 Protein
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SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) protein (His tag)
SOX2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 129-317) protein (His-IF2DI Tag)SOX2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-200) protein (His tag)SOX2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 155-245) protein (GST tag)SOX2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) protein (GST tag)SOX2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-319) protein (Strep Tag)Crystallography grade SOX2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
SRY (Sex Determining Region Y)-Box 2 (SOX2) protein (Myc-DYKDDDDK Tag)SOX2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
- Alternative Name
- SOX2 (SOX2 Products)
- Synonyms
- ANOP3 Protein, MCOPS3 Protein, RGD1565646 Protein, Sox-2 Protein, lcc Protein, ysb Protein, cb236 Protein, wu:fb83g04 Protein, wu:fc14d07 Protein, zgc:65860 Protein, zgc:77389 Protein, SRY-box2 Protein, Xsox-2 Protein, anop3 Protein, mcops3 Protein, sox-2 Protein, SRY-box 2 Protein, SRY box 2 Protein, SRY (sex determining region Y)-box 2 Protein, SRY-box 2 S homeolog Protein, SOX2 Protein, Sox2 Protein, sox2 Protein, sox2.S Protein
- Background
- Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in bryonic development such as YES1, FGF4, UTF1 and ZFP206 . Critical for early bryogenesis and for bryonic st cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural st cell self-renewal . Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation .
- Molecular Weight
- 50.3 kDa
- UniProt
- P48431
- Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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