WT1 Protein (AA 1-449, full length)

Catalog No. ABIN5710628

This Recombinant WT1 protein is produced in Escherichia coli (E. coli).

Quick Overview for WT1 Protein (AA 1-449, full length) (ABIN5710628)

Target: WT1 (Wilms Tumor 1 (WT1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Product Details

Protein Characteristics: AA 1-449, full length

Purpose: Recombinant Human Wilms tumor protein(WT1)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1-2 mg/mL

Storage: -20 °C,-80 °C

Storage Comment: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Expiry Date: 6-12 months

Target Details

Target: WT1 (Wilms Tumor 1 (WT1))

Alternative Name: WT1

Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital syst. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

Pathways: Tube Formation