Indian Hedgehog Protein (IHH) (AA 203-411) (His tag)

Catalog No. ABIN5711311

This Recombinant Indian Hedgehog protein is produced in Escherichia coli (E. coli).

Quick Overview for Indian Hedgehog Protein (IHH) (AA 203-411) (His tag) (ABIN5711311)

Target: Indian Hedgehog (IHH)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: AA 203-411

Purification tag / Conjugate: This Indian Hedgehog protein is labelled with His tag.

Sequence: CFPAGAQVRL ESGARVALSA VRPGDRVLAM GEDGSPTFSD VLIFLDREPH RLRAFQVIET QDPPRRLALT PAHLLFTADN HTEPAARFRA TFASHVQPGQ YVLVAGVPGL QPARVAAVST HVALGAYAPL TKHGTLVVED VVASCFAAVA DHHLAQLAFW PLRLFHSLAW GSWTPGEGVH WYPQLLYRLG RLLLEEGSFH PLGMSGAGS

Purification: SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: Indian Hedgehog (IHH)

Alternative Name: IHH

Background: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) .

Molecular Weight: 26.7 kDa

UniProt: Q14623

Pathways: Hedgehog Signaling