Indian Hedgehog Protein (IHH) (AA 1-135) (His tag)

Catalog No. ABIN7505521

This Recombinant Indian Hedgehog protein is produced in Escherichia coli (E. coli).

Quick Overview for Indian Hedgehog Protein (IHH) (AA 1-135) (His tag) (ABIN7505521)

Target: Indian Hedgehog (IHH)

Protein Type: Recombinant

Origin: Rat

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 1-135

Purification tag / Conjugate: This Indian Hedgehog protein is labelled with His tag.

Sequence: Met 1-Gly 135

Characteristics: A DNA sequence encoding the Rat Ihh protein (Q9WV29) (Met 1-Gly 135) was expressed with a N-His tag.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: Indian Hedgehog (IHH)

Alternative Name: Ihh

Background:

Abbreviation: Ihh

Target Synonym: IHH,Indian hedgehog homolo,Ihh

Background: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP).

Molecular Weight:

Calculated MW: 14.74 kDa

Observed MW: 15 kDa

UniProt: Q9WV29

Pathways: Hedgehog Signaling