BPHL Protein (AA 1-274, Isoform 2) (His-SUMO Tag)

Catalog No. ABIN5711487

Recombinant BPHL protein expressed in Escherichia coli (E. coli).

Quick Overview for BPHL Protein (AA 1-274, Isoform 2) (His-SUMO Tag) (ABIN5711487)

Target: BPHL (Biphenyl Hydrolase-Like (Serine Hydrolase) (BPHL))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: Isoform 2, AA 1-274

Purification tag / Conjugate: This BPHL protein is labelled with His-SUMO Tag.

Sequence: MPRNLLYSLL SSHLSPHFST SVTSAKVAVN GVQLHYQQTG EGDHAVLLLP GMLGSGETDF GPQLKNLNKK LFTVVAWDPR GYGHSRPPDR DFPADFFERD AKDAVDLMKA LKFKKVSLLG WSDGGITALI AAAKYPSYIH KMVIWGANAY VTDEDSMIYE GIRDVSKWSE RTRKPLEALY GYDYFARTCE KWVDGIRQFK HLPDGNICRH LLPRVQCPAL IVHGEKDPLV PRFHADFIHK HVKGSRLHLM PEGKHNLHLR FADEFNKLAE DFLQ

Purification: SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: BPHL (Biphenyl Hydrolase-Like (Serine Hydrolase) (BPHL))

Alternative Name: BPHL

Background: Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirent for the leaving group other than preferring a primary alcohol.

Molecular Weight: 47.1 kDa

UniProt: Q86WA6