BPHL Protein (His tag)

Catalog No. ABIN7317210

This Recombinant BPHL protein is expressed in Escherichia coli (E. coli).

Quick Overview for BPHL Protein (His tag) (ABIN7317210)

Target: BPHL (Biphenyl Hydrolase-Like (Serine Hydrolase) (BPHL))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This BPHL protein is labelled with His tag.

Purpose: Recombinant Human BPHL Protein (His Tag)

Sequence: Ser38-Gln291

Characteristics: A DNA sequence encoding the mature form of human BPHL (Q86WA6-1) (Ser38-Gln291) was expressed with a polyhistide tag at the N-terminus.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 50 mM NaCl, 10 % glycerol, pH 8.0

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: BPHL (Biphenyl Hydrolase-Like (Serine Hydrolase) (BPHL))

Alternative Name: BPHL

Background:

Background: BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. BPHL also activates valacyclovir to acyclovir. It may play a role in detoxification processes.

Synonym: BPH-RP,MCNAA,VACVASE

Molecular Weight: 30.7 kDa