BPHL Protein (His tag)
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- Target See all BPHL Proteins
- BPHL (Biphenyl Hydrolase-Like (Serine Hydrolase) (BPHL))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BPHL protein is labelled with His tag.
- Purpose
- Recombinant Human BPHL Protein (His Tag)
- Sequence
- Ser38-Gln291
- Characteristics
- A DNA sequence encoding the mature form of human BPHL (Q86WA6-1) (Ser38-Gln291) was expressed with a polyhistide tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product BPHL Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 50 mM NaCl, 10 % glycerol, pH 8.0
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- BPHL (Biphenyl Hydrolase-Like (Serine Hydrolase) (BPHL))
- Alternative Name
- BPHL (BPHL Products)
- Synonyms
- 2010012D11Rik Protein, 5730533B08Rik Protein, AI115341 Protein, BPH-RP Protein, MCNAA Protein, VACVASE Protein, biphenyl hydrolase like Protein, biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen) Protein, Bphl Protein, BPHL Protein
- Background
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Background: BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. BPHL also activates valacyclovir to acyclovir. It may play a role in detoxification processes.
Synonym: BPH-RP,MCNAA,VACVASE
- Molecular Weight
- 30.7 kDa
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