Kallikrein 7 Protein (KLK7) (AA 28-253)

Catalog No. ABIN5713584

This Recombinant Kallikrein 7 protein is expressed in Yeast.

Quick Overview for Kallikrein 7 Protein (KLK7) (AA 28-253) (ABIN5713584)

Target: Kallikrein 7 (KLK7)

Protein Type: Recombinant

Origin: Human

Source: Yeast

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: AA 28-253

Sequence: HHSSGLVPRG SHMDDDDKII DGAPCARGSH PWQVALLSGN QLHCGGVLVN ERWVLTAAHC KMNEYTVHLG SDTLGDRRAQ RIKASKSFRH PGYSTQTHVN DLMLVKLNSQ ARLSSMVKKV RLPSRCEPPG TTCTVSGWGT TTSPDVTFPS DLMCVDVKLI SPQDCTKVYK DLLENSMLCA GIPDSKKNAC NGDSGGPLVC RGTLQGLVSW GTFPCGQPND PGVYTQVCKF TKWINDTMKK HR

Purification: SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: Kallikrein 7 (KLK7)

Alternative Name: KLK7

Background: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.

Molecular Weight: 26.4 kDa

UniProt: P49862

Pathways: Complement System