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Cathepsin Z Protein (CTSZ) (AA 62-303) (His tag)

Recombinant Cathepsin Z protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN5853241

Quick Overview for Cathepsin Z Protein (CTSZ) (AA 62-303) (His tag) (ABIN5853241)

Target

See all Cathepsin Z (CTSZ) Proteins
Cathepsin Z (CTSZ)

Protein Type

Recombinant

Origin

  • 10
  • 5
  • 1
  • 1
Human

Source

  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 % by SDS - PAGE
  • Protein Characteristics

    AA 62-303

    Purification tag / Conjugate

    This Cathepsin Z protein is labelled with His tag.

    Sequence

    MGSSHHHHHH SSGLVPRGSH MGSLPKSWDW RNVDGVNYAS ITRNQHIPQY CGSCWAHAST SAMADRINIK RKGAWPSTLL SVQNVIDCGN AGSCEGGNDL SVWDYAHQHG IPDETCNNYQ AKDQECDKFN QCGTCNEFKE CHAIRNYTLW RVGDYGSLSG REKMMAEIYA NGPISCGIMA TERLANYTGG IYAEYQDTTY INHVVSVAGW GISDGTEYWI VRNSWGEPWG ERGWLRIVTS TYKDGKGARY NLAIEEHCTF GDPIV
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Comment

    Denatured

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol, 0.4M urea

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target

    Cathepsin Z (CTSZ)

    Alternative Name

    CTSZ

    Background

    CTSZ is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. At least two transcript variants of this gene have been found, but the full-length nature of only one of them has been determined. Recombinant human CTSZ protein, fused to His-tag at N-terminus, was expressed in E.coli .

    Molecular Weight

    29.5 kDa (265aa)

    NCBI Accession

    NP_001327

    UniProt

    Q9UBR2

    Pathways

    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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