Cathepsin Z Protein (CTSZ) (AA 62-303) (His tag)
Quick Overview for Cathepsin Z Protein (CTSZ) (AA 62-303) (His tag) (ABIN5853241)
Target
See all Cathepsin Z (CTSZ) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 62-303
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Purification tag / Conjugate
- This Cathepsin Z protein is labelled with His tag.
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Sequence
- MGSSHHHHHH SSGLVPRGSH MGSLPKSWDW RNVDGVNYAS ITRNQHIPQY CGSCWAHAST SAMADRINIK RKGAWPSTLL SVQNVIDCGN AGSCEGGNDL SVWDYAHQHG IPDETCNNYQ AKDQECDKFN QCGTCNEFKE CHAIRNYTLW RVGDYGSLSG REKMMAEIYA NGPISCGIMA TERLANYTGG IYAEYQDTTY INHVVSVAGW GISDGTEYWI VRNSWGEPWG ERGWLRIVTS TYKDGKGARY NLAIEEHCTF GDPIV
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Denatured
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.4M urea
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Cathepsin Z (CTSZ)
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Alternative Name
- CTSZ
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Background
- CTSZ is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. At least two transcript variants of this gene have been found, but the full-length nature of only one of them has been determined. Recombinant human CTSZ protein, fused to His-tag at N-terminus, was expressed in E.coli .
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Molecular Weight
- 29.5 kDa (265aa)
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NCBI Accession
- NP_001327
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UniProt
- Q9UBR2
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Pathways
- Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
Target
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