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Cathepsin Z Protein (CTSZ) (AA 24-303) (His tag)

CTSZ Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1096251
  • Target See all Cathepsin Z (CTSZ) Proteins
    Cathepsin Z (CTSZ)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 24-303
    Origin
    • 8
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Cathepsin Z protein is labelled with His tag.
    Purpose
    Recombinant Human Cathepsin Z/CTSZ (C-6His)
    Sequence
    GLYFRRGQTC YRPLRGDGLA PLGRSTYPRP HEYLSPADLP KSWDWRNVDG VNYASITRNQ HIPQYCGSCW AHASTSAMAD RINIKRKGAW PSTLLSVQNV IDCGNAGSCE GGNDLSVWDY AHQHGIPDET CNNYQAKDQE CDKFNQCGTC NEFKECHAIR NYTLWRVGDY GSLSGREKMM AEIYANGPIS CGIMATERLA NYTGGIYAEY QDTTYINHVV SVAGWGISDG TEYWIVRNSW GEPWGERGWL RIVTSTYKDG KGARYNLAIE EHCTFGDPIV VDHHHHHH
    Characteristics

    Recombinant Human Cathepsin Z/CTSZ (C-6His)

    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CTSZ Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.0.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    -80 °C
    Storage Comment
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Cathepsin Z (CTSZ)
    Alternative Name
    Cathepsin Z (CTSZ Products)
    Synonyms
    wu:fj81f10 Protein, zgc:103420 Protein, CTSZ Protein, CTSX Protein, AI787083 Protein, AU019819 Protein, D2Wsu143e Protein, CATX Protein, CathePsin Z Protein, cathepsin Z Protein, cathepsin Z S homeolog Protein, papain family cysteine protease Protein, cpz-1 Protein, cpz-2 Protein, CTSZ Protein, ctsz Protein, ctsz.S Protein, TTHERM_00102779 Protein, NAEGRDRAFT_78125 Protein, Ctsz Protein
    Background
    Recombinant Human Cathepsin Z produced by transfected human cells is a secreted protein with sequence (Gly24-Val303) of Human CTSZ fused with a polyhistidine tag at the C-terminus.
    Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence, a propeptide and a mature chain. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B, it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system, predominantly monocytes, macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family, Cathepsin Z may be involved in tumorigenesis.
    Molecular Weight
    32.51 kDa
    UniProt
    Q9UBR2
    Pathways
    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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