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Cathepsin Z Protein (CTSZ) (His tag)

CTSZ Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319393
  • Target See all Cathepsin Z (CTSZ) Proteins
    Cathepsin Z (CTSZ)
    Protein Type
    Recombinant
    Origin
    • 8
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Cathepsin Z protein is labelled with His tag.
    Purpose
    Recombinant Human Cathepsin Z Protein (His Tag)
    Sequence
    Gly24-Val303
    Characteristics
    Recombinant Human Cathepsin Z is produced by our Mammalian expression system and the target gene encoding Gly24-Val303 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CTSZ Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    Cathepsin Z (CTSZ)
    Alternative Name
    Cathepsin Z (CTSZ Products)
    Synonyms
    wu:fj81f10 Protein, zgc:103420 Protein, CTSZ Protein, CTSX Protein, AI787083 Protein, AU019819 Protein, D2Wsu143e Protein, CATX Protein, CathePsin Z Protein, cathepsin Z Protein, cathepsin Z S homeolog Protein, papain family cysteine protease Protein, cpz-1 Protein, cpz-2 Protein, CTSZ Protein, ctsz Protein, ctsz.S Protein, TTHERM_00102779 Protein, NAEGRDRAFT_78125 Protein, Ctsz Protein
    Background

    Background: Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence, a propeptide and a mature chain. It exhibits bothcarboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B, it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system, predominantly monocytes, macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family, Cathepsin Z may be involved in tumorigenesis.

    Synonym: Cathepsin Z, Cathepsin P, Cathepsin X, CTSZ

    Molecular Weight
    32.5 kDa
    UniProt
    Q9UBR2
    Pathways
    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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