eEF1A1 Protein (AA 1-462)

Catalog No. ABIN5853616

Product Details

Target: eEF1A1 (EEF1A1) (Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1))

Protein Type: Recombinant

Protein Characteristics: AA 1-462

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MGKEKTHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAAEMG KGSFKYAWVL DKLKAERERG ITIDISLWKF ETSKYYVTII DAPGHRDFIK NMITGTSQAD CAVLIVAAGV GEFEAGISKN GQTREHALLA YTLGVKQLIV GVNKMDSTEP PYSQKRYEEI VKEVSTYIKK IGYNPDTVAF VPISGWNGDN MLEPSANMPW FKGWKVTRKD GNASGTTLLE ALDCILPPTR PTDKPLRLPL QDVYKIGGIG TVPVGRVETG VLKPGMVVTF APVNVTTEVK SVEMHHEALS EALPGDNVGF NVKNVSVKDV RRGNVAGDSK NDPPMEAAGF TAQVIILNHP GQISAGYAPV LDCHTAHIAC KFAELKEKID RRSGKKLEDG PKFLKSGDAA IVDMVPGKPM CVESFSDYPP LGRFAVRDMR QTVAVGVIKA VDKKAAGAGK ITKSAQKAQK AK

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Denatured

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: eEF1A1 (EEF1A1) (Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1))

Alternative Name: EEF1A1 (EEF1A1 Products)

Synonyms: CCS-3 Protein, CCS3 Protein, EE1A1 Protein, EEF-1 Protein, EEF1A Protein, EF-Tu Protein, EF1A Protein, GRAF-1EF Protein, HNGC:16303 Protein, LENG7 Protein, PTI1 Protein, eEF1A-1 Protein, Eef1a2 Protein, Eef1a2l1 Protein, SI Protein, EEF1A2 Protein, EF1A1 Protein, eef1a1 Protein, wu:fj34g08 Protein, zgc:110335 Protein, EEF1A1 Protein, RABEFLA2 Protein, EFL1-alpha Protein, chunp6927 Protein, eef1a Protein, ef1a Protein, ik:tdsubc_2a3 Protein, ik:tdsubc_2b3 Protein, tdsubc_2a3 Protein, wu:fa91c07 Protein, wu:fa94b03 Protein, wu:fi13b09 Protein, xx:tdsubc_2a3 Protein, xx:tdsubc_2b3 Protein, EF-1A Protein, EF-1-ALPHA-S Protein, eef1a-s Protein, eef1as Protein, fj64c02 Protein, wu:fj64c02 Protein, zgc:73138 Protein, eukaryotic translation elongation factor 1 alpha 1 Protein, eukaryotic translation elongation factor 1 alpha 1b Protein, eukaryotic translation elongation factor 1 alpha 1, like 1 Protein, eukaryotic translation elongation factor 1 alpha 1 L homeolog Protein, elongation factor 1-alpha Protein, eukaryotic translation elongation factor 1 alpha 1a Protein, EEF1A1 Protein, Eef1a1 Protein, eef1a1b Protein, eef1a1l1 Protein, eef1a1.L Protein, tufA Protein, eef1a1a Protein

Background: EEF1A1 is an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66 % of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. Recombinant human EEF1A1 protein is expressed in E.coli.

Molecular Weight: 50 kDa (462aa)

NCBI Accession: NP_001393

UniProt: P68104