ACTR3 Protein (AA 1-418) (His tag)

Catalog No. ABIN5853908

This Recombinant ACTR3 protein is produced in Escherichia coli (E. coli).

Quick Overview for ACTR3 Protein (AA 1-418) (His tag) (ABIN5853908)

Target: ACTR3 (ARP3 Actin-Related Protein 3 (ACTR3))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 85 %

Product Details

Protein Characteristics: AA 1-418

Purification tag / Conjugate: This ACTR3 protein is labelled with His tag.

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAGRLPA CVVDCGTGYT KLGYAGNTEP QFIIPSCIAI KESAKVGDQA QRRVMKGVDD LDFFIGDEAI EKPTYATKWP IRHGIVEDWD LMERFMEQVI FKYLRAEPED HYFLLTEPPL NTPENREYTA EIMFESFNVP GLYIAVQAVL ALAASWTSRQ VGERTLTGTV IDSGDGVTHV IPVAEGYVIG SCIKHIPIAG RDITYFIQQL LRDREVGIPP EQSLETAKAV KERYSYVCPD LVKEFNKYDT DGSKWIKQYT GINAISKKEF SIDVGYERFL GPEIFFHPEF ANPDFTQPIS EVVDEVIQNC PIDVRRPLYK NIVLSGGSTM FRDFGRRLQR DLKRTVDARL KLSEELSGGR LKPKPIDVQV ITHHMQRYAV WFGGSMLAST PEFYQVCHTK KDYEEIGPSI CRHNPVFGVM S

Purification: > 85% by SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Denatured

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: ACTR3 (ARP3 Actin-Related Protein 3 (ACTR3))

Alternative Name: ACTR3

Background: The specific function of ACTR3 has not yet been determined, however, this protein is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. Recombinant human ACTR3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Molecular Weight: 49.8 kDa (441aa)

NCBI Accession: NP_005712

Pathways: RTK Signaling, Regulation of Actin Filament Polymerization