DDR2 Protein (AA 22-399) (His tag)

Catalog No. ABIN5854620

This Recombinant DDR2 protein is expressed in Baculovirus infected Insect Cells.

Quick Overview for DDR2 Protein (AA 22-399) (His tag) (ABIN5854620)

Target: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: SDS-PAGE (SDS)

Purity: > 90% by SDS-PAGE

Product Details

Protein Characteristics: AA 22-399

Purification tag / Conjugate: This DDR2 protein is labelled with His tag.

Sequence: KAQVNPAICR YPLGMSGGQI PDEDITASSQ WSESTAAKYG RLDSEEGDGA WCPEIPVEPD DLKEFLQIDL HTLHFITLVG TQGRHAGGHG IEFAPMYKIN YSRDGTRWIS WRNRHGKQVL DGNSNPYDIF LKDLEPPIVA RFVRFIPVTD HSMNVCMRVE LYGCVWLDGL VSYNAPAGQQ FVLPGGSIIY LNDSVYDGAV GYSMTEGLGQ LTDGVSGLDD FTQTHEYHVW PGYDYVGWRN ESATNGYIEI MFEFDRIRNF TTMKVHCNNM FAKGVKIFKE VQCYFRSEAS EWEPNAISFP LVLDDVNPSA RFVTVPLHHR MASAIKCQYH FADTWMMFSE ITFQSDAAMY NNSEALPTSP MAPTTYDPML KVDDSNTR

Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details

Target: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Alternative Name: DDR2

Background: DDR2, also known as discoidin domain-containing receptor 2, belongs to the discoidin-like domain containing subfamily of receptor tyrosine kinases. It is mainly expressed in mesenchymal cells and is unique amog RTKs in that its ligand is fibrillar collagen rather than a growth factor-like peptide. Recombinant human DDR2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 43.7 kDa (386aa)

NCBI Accession: NP_001014796

UniProt: Q16832

Pathways: RTK Signaling