TIM3 Protein (AA 22-202) (hIgG-His-tag)
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- Target See all TIM3 (TIM 3) Proteins
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-202
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This TIM3 protein is labelled with hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADLSEVEYRA EVGQNAYLPC FYTPAAPGNL VPVCWGKGAC PVFECGNVVL RTDERDVNYW TSRYWLNGDF RKGDVSLTIE NVTLADSGIY CCRIQIPGIM NDEKFNLKLV IKPAKVTPAP TRQRDFTAAF PRMLTTRGHG PAETQTLGSL PDINLTQIST LANELRDSRL ANDLRDSGAT IRIGLEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSRDELTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGKHHH HHH
- Purity
- > 85% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product TIM 3 Protein
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Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-200) protein (His tag)
TIM 3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) protein (mFc-His Tag)TIM 3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-200) protein (His-Avi Tag,Biotin)TIM 3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-191) protein (His tag)TIM 3 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-200) (Active) protein (His tag,AVI tag,Biotin)TIM 3 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Hepatitis A Virus Cellular Receptor 2 (TIM 3) protein (His tag)TIM 3 Origin: Marmoset Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (Active) protein (Fc Tag)TIM 3 Origin: Mouse Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 20-191) protein (His tag)TIM 3 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Hepatitis A Virus Cellular Receptor 2 (TIM 3) protein (Fc Tag)TIM 3 Origin: Cynomolgus Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 20-193) protein (His tag)TIM 3 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- Alternative Name
- TIM-3/HAVCR2 (TIM 3 Products)
- Background
- HAVCR2, also known as hepatitis A virus cellular receptor 2, is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not on Th2 cells. It was the first surface molecule that specificallyidentifies Th1 cells in both mice and human. It interactions with Galectin-9 can alternatively trigger immune stimulatory effects, such as the coactivation of NK cell cytotoxicity. Recombinant human HAVCR2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 47.3 kDa (423aa)
- NCBI Accession
- NP_116171
- UniProt
- Q8TDQ0
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
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