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Kallikrein 5 Protein (KLK5) (AA 67-293) (His tag)

KLK5 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN5854782
  • Target See all Kallikrein 5 (KLK5) Proteins
    Kallikrein 5 (KLK5)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 67-293
    Origin
    • 7
    • 3
    Human
    Source
    • 4
    • 3
    • 2
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This Kallikrein 5 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    ADLIINGSDC DMHTQPWQAA LLLRPNQLYC GAVLVHPQWL LTAAHCRKKV FRVRLGHYSL SPVYESGQQM FQGVKSIPHP GYSHPGHSND LMLIKLNRRI RPTKDVRPIN VSSHCPSAGT KCLVSGWGTT KSPQVHFPKV LQCLNISVLS QKRCEDAYPR QIDDTMFCAG DKAGRDSCQG DSGGPVVCNG SLQGLVSWGD YPCARPNRPG VYTNLCKFTK WIQETIQANS HHHHHH
    Purity
    > 95 % by SDS - PAGE
    Endotoxin Level
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Top Product
    Discover our top product KLK5 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    Kallikrein 5 (KLK5)
    Alternative Name
    KLK5 (KLK5 Products)
    Synonyms
    KLK-L2 Protein, KLKL2 Protein, SCTE Protein, 1110030O19Rik Protein, KAL Protein, KALA Protein, Klk1 Protein, Klk5 Protein, RATKALA Protein, kallikrein related peptidase 5 Protein, kallikrein related-peptidase 5 Protein, kallikrein 5-like Protein, KLK5 Protein, Klk5 Protein, Klk5l Protein
    Background
    KLK5, also known as kallikrein-5, is one of the newly identified members of the kallikrein gene family, which is a subgroup of the serine protease enzyme family. It is highly expressed in skin, mammary gland and testis. KLK5 has been suggested to regulate cell shedding (desquamation) in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. It is proposed that KLK5 regulates this process since it is able to self-activate in addition to activating KLK7 and KLK14. Recombinant human KLK5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    26.2kDa (236aa) 28-40kDa (SDS-PAGE under reducing conditions)
    NCBI Accession
    NP_001070960
    UniProt
    Q9Y337
    Pathways
    Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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