Kallikrein 5 Protein (KLK5) (Transcript Variant 2) (His tag)
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- Target See all Kallikrein 5 (KLK5) Proteins
- Kallikrein 5 (KLK5)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Kallikrein 5 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human KLK5 / Kallikrein-5 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- < 0.1 EU per μg protein as determined by LAL test
- Top Product
- Discover our top product KLK5 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 20 mM MES, 150 mM NaCl, 10 % Glycerol, pH 5.5. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Kallikrein 5 (KLK5)
- Alternative Name
- Klk5,kallikrein-5 (KLK5 Products)
- Synonyms
- KLK-L2 Protein, KLKL2 Protein, SCTE Protein, 1110030O19Rik Protein, KAL Protein, KALA Protein, Klk1 Protein, Klk5 Protein, RATKALA Protein, kallikrein related peptidase 5 Protein, kallikrein related-peptidase 5 Protein, kallikrein 5-like Protein, KLK5 Protein, Klk5 Protein, Klk5l Protein
- Background
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
- Molecular Weight
- 30.6 kDa
- NCBI Accession
- NP_001070959
- Pathways
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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