CD79b Protein (AA 29-159) (His tag)

Catalog No. ABIN7281213

This Recombinant CD79b protein is produced in Baculovirus infected Insect Cells.

Quick Overview for CD79b Protein (AA 29-159) (His tag) (ABIN7281213)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: SDS-PAGE (SDS)

Purity: > 90 % by SDS - PAGE

Product Details

Protein Characteristics: AA 29-159

Purification tag / Conjugate: This CD79b protein is labelled with His tag.

Sequence: ADPARSEDRY RNPKGSACSR IWQSPRFIAR KRGFTVKMHC YMNSASGNVS WLWKQEMDEN PQQLKLEKGR MEESQNESLA TLTIQGIRFE DNGIYFCQQK CNNTSEVYQG CGTELRVMGF STLAQLKQRN TLKDHHHHHH

Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79B

Background: CD79B, as known as B-cell antigen receptor complex-associated protein beta chain isoform 1, is B-cell-specific glycoprotein B29. It is a single-pass type 1 membrane protein containing one Ig-like V-type domain and one ITAM domain. This protein is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR). CD79A and B proteins are required for BCR-meditated signaling and consequently for the development and activation of B lineage cells. Recombinant human CD79B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 16.3kDa (140aa) 18-28kDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_000617

UniProt: P40259

Pathways: BCR Signaling