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CD79b Protein (Fc Tag)

CD79B Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Catalog No. ABIN7321126
  • Target See all CD79b (CD79B) Proteins
    CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
    Protein Type
    Recombinant
    Origin
    • 18
    • 5
    • 2
    • 2
    • 1
    Rat
    Source
    • 13
    • 6
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD79b protein is labelled with Fc Tag.
    Purpose
    Recombinant Rat CD79B/B29 Protein (Fc Tag)
    Sequence
    Met1-Asp158
    Characteristics
    A DNA sequence encoding the rat CD79B (O70153) (Met1-Asp158) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
    Purity
    > 90 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product CD79B Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
    Alternative Name
    CD79B/B29 (CD79B Products)
    Synonyms
    B29 Protein, Ig-beta Protein, Igb Protein, Igbeta Protein, AGM6 Protein, IGB Protein, CD79B antigen Protein, CD79b molecule Protein, Cd79b Protein, CD79B Protein
    Background

    Background: CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.

    Synonym: CD79B,B29/Ig-beta,Igb

    Molecular Weight
    42.2 kDa
    UniProt
    O70153
    Pathways
    BCR Signaling
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