CD79b Protein (Fc Tag)
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- Target See all CD79b (CD79B) Proteins
- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
- Protein Type
- Recombinant
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Origin
- Rat
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD79b protein is labelled with Fc Tag.
- Purpose
- Recombinant Rat CD79B/B29 Protein (Fc Tag)
- Sequence
- Met1-Asp158
- Characteristics
- A DNA sequence encoding the rat CD79B (O70153) (Met1-Asp158) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 90 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product CD79B Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
- Alternative Name
- CD79B/B29 (CD79B Products)
- Synonyms
- B29 Protein, Ig-beta Protein, Igb Protein, Igbeta Protein, AGM6 Protein, IGB Protein, CD79B antigen Protein, CD79b molecule Protein, Cd79b Protein, CD79B Protein
- Background
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Background: CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.
Synonym: CD79B,B29/Ig-beta,Igb
- Molecular Weight
- 42.2 kDa
- UniProt
- O70153
- Pathways
- BCR Signaling
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