IL1A Protein (AA 113-271) (His tag)
Quick Overview for IL1A Protein (AA 113-271) (His tag) (ABIN5855196)
Target
See all IL1A ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 113-271
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Purification tag / Conjugate
- This IL1A protein is labelled with His tag.
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Sequence
- MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSA PFSFLSNVKY NFMRIIKYEF ILNDALNQSI IRANDQYLTA AALHNLDEAV KFDMGAYKSS KDDAKITVIL RISKTQLYVT AQDEDQPVLL KEMPEIPKTI TGSETNLLFF WETHGTKNYF TSVAHPNLFI ATKQDYWVCL AGGPPSITDF QILENQA
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Characteristics
- IL-1, alpha, 113-271aa, Human, His-tagged, Recombinant, E.coli
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in 20mM Tris-HCl pH 7.5, 10% glycerol
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- IL1A (Interleukin 1 alpha (IL1A))
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Alternative Name
- IL-1 alpha/IL1A
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Background
- IL-1 consists of two distinct forms, IL-1 alpha and IL-1 beta which perform the same functions but are distinct proteins. IL-1alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is also temporarily upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. Recombinant IL-1a protein was expressed in E. coli and purified by using conventional chromatography techniques.
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Molecular Weight
- 22.4 kDa (197aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_000566
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Pathways
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
Target
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