KIT Ligand Protein (KITLG) (AA 26-189)

Catalog No. ABIN620998

This Recombinant KIT Ligand protein is produced in .

Quick Overview for KIT Ligand Protein (KITLG) (AA 26-189) (ABIN620998)

Target: KIT Ligand (KITLG)

Protein Type: Recombinant

Origin: Rat

Host: Please inquire

Purity: > 98.0 % as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Product Details

Protein Characteristics: AA 26-189

Sequence: MQEICRNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV THLSVSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVAC MEENAPKNVK ESLKKPETRN FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA.

Characteristics: Recombinant Rat Stem Cell Factor

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a concentrated (1mg/ml) solution in water containing 0.02% NaHCO3.It is recommended to reconstitute the lyophilized SCF in sterile 18M -cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Storage: -20 °C

Target Details

Target: KIT Ligand (KITLG)

Alternative Name: Stem Cell Factor

Background: Stem cell factor Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 164 amino acids (26-189) and having a molecular mass of 18.4 kDa. The Rat SCF is purified by proprietary chromatographic techniques. Introduction: Stem cell factor / KIT ligand (SCF) is a cytokine which binds CD117 (c-Kit). SCF is also known as ,steel factor, or ,c-kit ligand,. SCF exists in two forms, cell surface bound SCF and soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases. SCF is a growth factor important for the survival, proliferation, and differentiation of hematopoietic stem cells and other hematopoietic progenitor cells. One of its roles is to change the BFU-E (burst-forming unit-erythroid) cells, which are the earliest erythrocyte precursors in the erythrocytic series, into the CFU-E (colony-forming unit-erythroid). Synonyms: Kit ligand Precursor, C-kit ligand, SCF, Mast cell growth factor, MGF, SF, KL-1, Kitl, DKFZp686F2250, Hematopoietic growth factor KL.

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway