Complement C3b Protein
C3b
Origin: Human
Host: Human
Native
> 90 %. By SDS-PAGE
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- Target See all Complement C3b (C3b) products
- Complement C3b (C3b) (Complement C3 beta Chain (C3b))
- Protein Type
- Native
- Origin
- Human
- Source
- Human
- Characteristics
- Native Human C3b
- Purification
- Purified C3b from human serum
- Purity
- > 90 %. By SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml
- Buffer
- Phosphate buffered saline, pH 7.2
- Storage
- -20 °C
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- Target
- Complement C3b (C3b) (Complement C3 beta Chain (C3b))
- Alternative Name
- C3b (C3b Products)
- Synonyms
- AHUS5 Protein, ARMD9 Protein, ASP Protein, C3a Protein, C3b Protein, CPAMD1 Protein, AI255234 Protein, HSE-MSF Protein, Plp Protein, complement C3 Protein, complement component 3 Protein, C3 Protein
- Background
- Cleavage of the C3-alpha chain at peptide bond 77 results in production of C3a and C3b fragments. The C3b fragment is a glycoprotein composed of the modified C3-alpha chain and the intact C3-beta chain. Nascent C3b has the transient ability to form a covalent ester bond with a variety of target surfaces. Once bound to target surfaces C3b becomes an essential subunit of both the classical and alternative pathway C5 cleaving enzymes.
- Molecular Weight
- 180 kDa
- Pathways
- Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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