IL1RL1 Protein (AA 27-342) (Fc Tag)
Quick Overview for IL1RL1 Protein (AA 27-342) (Fc Tag) (ABIN6253430)
Target
See all IL1RL1 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 27-342
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Purification tag / Conjugate
- This IL1RL1 protein is labelled with Fc Tag.
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Purpose
- IL-33R (mouse):Fc (mouse) (rec.)
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Specificity
- The extracellular domain of mouse IL-33R [ST2] (aa 27-342) is fused to the N-terminus of the Fc region of mouse IgG2a.
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Characteristics
- Protein. The extracellular domain of mouse IL-33R [ST2] (aa 27-342) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). Receptor for interleukin-33 (IL-33). Its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14 and MAPK8 by similarity. Possibly involved in helper T cell function.
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Endotoxin Level
- <0.06EU/μg protein (LAL test, Lonza).
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Biological Activity Comment
- Measured by its ability to bind recombinant mouse IL-33 in a functional ELISA.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized from 0.2μm-filtered solution in PBS.
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Handling Advice
- Avoid freeze/thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
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Alternative Name
- IL-33R
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Background
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Alternate Names/Synonyms: Interleukin-33 Receptor, IL1RL1, DER4, ST2
Product Description: Receptor for interleukin-33 (IL-33). Its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14 and MAPK8 by similarity. Possibly involved in helper T cell function.
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NCBI Accession
- NP_001020773
Target
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