DNER Protein (AA 29-637, Extracellular Domain) (Fc Tag)
Quick Overview for DNER Protein (AA 29-637, Extracellular Domain) (Fc Tag) (ABIN6253492)
Target
See all DNER ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 29-637, Extracellular Domain
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Purification tag / Conjugate
- This DNER protein is labelled with Fc Tag.
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Purpose
- DNER (extracellular domain) (human):Fc (human) (rec.)
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Specificity
- The extracellular domain of human DNER (aa 29-637) is fused at the C-terminus to the Fc portion of human IgG1.
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Cross-Reactivity
- Human
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Characteristics
- The extracellular domain of human DNER (aa 29-637) is fused at the C-terminus to the Fc portion of human IgG1.
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Sterility
- Sterile filtered
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Endotoxin Level
- <0.06EU/μg purified protein (LAL test).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized from 0.2μm-filtered solution in PBS.
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Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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Expiry Date
- 6 months
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- DNER (delta/notch-Like EGF Repeat Containing (DNER))
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Alternative Name
- DNER
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Background
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BET, UNQ262/PRO299, Delta and Notch-like Epidermal Growth Factor-related Receptor
DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis.
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Molecular Weight
- ~120kDa (SDS-PAGE)
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NCBI Accession
- NP_620711
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Pathways
- Skeletal Muscle Fiber Development
Target
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