TNFRSF11A Protein (AA 30-212) (Fc Tag)
Quick Overview for TNFRSF11A Protein (AA 30-212) (Fc Tag) (ABIN6253593)
Target
See all TNFRSF11A ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 30-212
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Purification tag / Conjugate
- This TNFRSF11A protein is labelled with Fc Tag.
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Sequence
- AA 30-212
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Endotoxin Level
- Less than 0.1 EU per μg by the LAL method.
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Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 30-212) protein (Fc Tag)
TNFRSF11A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 31-214) protein (Fc Tag)TNFRSF11A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 30-212) protein (His-DYKDDDDK-Strep II Tag)TNFRSF11A Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) protein (His tag)TNFRSF11A Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 28-202) protein (His tag)TNFRSF11A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) protein (Fc Tag)TNFRSF11A Origin: Rat Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) protein (His tag)TNFRSF11A Origin: Rat Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 28-212) protein (hIgG-His-tag)TNFRSF11A Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 31-130) protein (GST tag)TNFRSF11A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
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Alternative Name
- RANK
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Background
- RANK / TNFRSF11A is a member of the tumor necrosis factor receptor family. RANK / TNFRSF11A shares significant amino acid homology with other members of the TNF R family in its extracellular four cysteine-rich repeats. Functional genomics in mice showed that RANKL (TNFSF11), a member of the TNF ligand superfamily, and RANK (TNFRSF11a), the cognate TNFR family receptor for RANKL, were essential for osteoclastogenesis in vivo. A functional interaction between RANKL, expressed by bone stromal cells of the osteoblast lineage, and RANK, expressed by osteoclast precursors of hematopoietic myeloid lineage, is necessary for osteoclast differentiation, survival, and activation.
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Molecular Weight
- 47.2 kDa
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NCBI Accession
- NP_003830
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Pathways
- NF-kappaB Signaling
Target
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