IL-18 Protein (AA 36-192)
Quick Overview for IL-18 Protein (AA 36-192) (ABIN6387557)
Target
See all IL-18 (IL18) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 36-192
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Sequence
- MNFGRLHCTT AVIRNINDQV LFVDKRQPVF EDMTDIDQSA SEPQTRLIIY MYKDSEVRGL AVTLSVKDSK MSTLSCKNKI ISFEEMDPPE NIDDIQSDLI FFQKRVPGHN KMEFESSLYE GHFLACQKED DAFKLILKKK DENGDKSVMF TLTNLHQS
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Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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Interleukin 18 (IL18) (AA 37-193) protein
IL18 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 (IL18) (AA 37-193) protein (Biotin)IL18 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Interleukin 18 (IL18) (AA 37-193) protein (His-IF2DI Tag)IL18 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 18 (IL18) (AA 36-192) protein (His tag)IL18 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Interleukin 18 (IL18) (AA 1-193) protein (GST tag)IL18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 18 (IL18) protein (His tag)IL18 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interleukin 18 (IL18) protein (GST tag)IL18 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % as determined by reducing SDS-PAGE.
Interleukin 18 (IL18) (AA 37-197) protein (Fc Tag)IL18 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 18 (IL18) (AA 37-197) protein (mFc Tag)IL18 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4)
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- IL-18 (IL18) (Interleukin 18 (IL18))
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Alternative Name
- IL-18
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Background
- IL18 (Interleukin18 ), previously known as interferon-gamma (IFN-gamma) -inducing factor, is an activator of NK cells and a co-inducer of Th1 cytokines. IL18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. Recombinant mouse IL18 was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
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Molecular Weight
- 18.2 kDa (158aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_032386
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UniProt
- P70380
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
Target
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