Cathepsin B Protein (CTSB) (AA 18-339) (His tag)
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- Target See all Cathepsin B (CTSB) Proteins
- Cathepsin B (CTSB)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 18-339
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Origin
- Mouse
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This Cathepsin B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS), Enzyme Activity Assay (EAA)
- Sequence
- HDKPSFHPLS DDLINYINKQ NTTWQAGRNF YNVDISYLKK LCGTVLGGPK LPGRVAFGED IDLPETFDAR EQWSNCPTIG QIRDQGSCGS CWAFGAVEAI SDRTCIHTNG RVNVEVSAED LLTCCGIQCG DGCNGGYPSG AWSFWTKKGL VSGGVYNSHV GCLPYTIPPC EHHVNGSRPP CTGEGDTPRC NKSCEAGYSP SYKEDKHFGY TSYSVSNSVK EIMAEIYKNG PVEGAFTVFS DFLTYKSGVY KHEAGDMMGG HAIRILGWGV ENGVPYWLAA NSWNLDWGDN GFFKILRGEN HCGIESEIVA GIPRTDQYWG RFLEHHHHHH
- Purity
- > 90% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Biological Activity Comment
- Specific activity is > 2,000pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of Z-Arg-Arg-AMC to Z-Arg-Arg and AMC per minute at pH 6.0 at 37C.
- Top Product
- Discover our top product CTSB Protein
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Cathepsin B (CTSB) protein (His tag)
CTSB Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Cathepsin B (CTSB) (AA 1-339) protein (GST tag)CTSB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cathepsin B (CTSB) (AA 21-339) protein (GST tag)CTSB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cathepsin B (CTSB) (AA 18-339) protein (His tag)CTSB Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
Cathepsin B (CTSB) (Active) protein (His tag)CTSB Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Cathepsin B (CTSB) protein (His tag)CTSB Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Cathepsin B (CTSB) (AA 82-333), (partial) protein (GST tag)CTSB Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
Cathepsin B (CTSB) (AA 18-339) protein (His tag)CTSB Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Bioactivity Validated
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- Cathepsin B (CTSB)
- Alternative Name
- Cathepsin B (CTSB Products)
- Background
- CTSB, also known as cathepsin B preproprotein, is a papain-family cysteine protease that is normally located in lysosomes. It has the ability to degrade several extracellular matrix components at both neutral and acidic pH and has been implicated in the progression of several human and rodent tumors progression and arthritis. Recombinant mouse CTSB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 36.4 kDa (330aa)
- NCBI Accession
- NP_031824
- UniProt
- P10605
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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