KIR2DL4/CD158d Protein (AA 24-242) (hIgG-His-tag)
KIR2DL4
Origin: Human
Host: Baculovirus infected Insect Cells
Recombinant
> 85 % by SDS - PAGE
SDS
1 image
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- Target See all KIR2DL4/CD158d (KIR2DL4) Proteins
- KIR2DL4/CD158d (KIR2DL4) (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-242
- Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This KIR2DL4/CD158d protein is labelled with hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- HVGGQDKPFC SAWPSAVVPQ GGHVTLRCHY RRGFNIFTLY KKDGVPVPEL YNRIFWNSFL ISPVTPAHAG TYRCRGFHPH SPTEWSAPSN PLVIMVTGLY EKPSLTARPG PTVRAGENVT LSCSSQSSFD IYHLSREGEA HELRLPAVPS INGTFQADFP LGPATHGETY RCFGSFHGSP YEWSDPSDPL PVSVTGNPSS SWPSPTEPSF KTGIARHLHL EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKHHHHHH
- Purity
- > 85 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product KIR2DL4 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- KIR2DL4/CD158d (KIR2DL4) (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4))
- Alternative Name
- KIR2DL4 (KIR2DL4 Products)
- Background
- KIR2DL4, also known as killer cell immunoglobulin-like receptor 2DL4, is a member of the killer cell Ig-like receptor (KIR) family. KIR proteins with the long cytoplasmic domain transduce inhibitory signals via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. This protein induces NK cells to produce IFN-gamma and stimulation with IL-2 upregulates cell surface expression on CD56dim cells and leads to the inhibition of the cytolytic NK cell function. Recombinant human KIR2DL4 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 51.0kDa (458aa) 50-70KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_002246
- UniProt
- Q99706
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