KIR2DL4/CD158d Protein
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- Target See all KIR2DL4/CD158d (KIR2DL4) Proteins
- KIR2DL4/CD158d (KIR2DL4) (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- CHO Cells
- Purpose
- Recombinant Human KIR2DL4/CD158D Protein
- Sequence
- Met 1-His242
- Characteristics
- A DNA sequence encoding the human KIR2DL4 (ADY38409.1)(Met1-His242) was expressed with six amino acids (LEVLFQ) at the C-terminus was expressed and purified.
- Purity
- > 85 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product KIR2DL4 Protein
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Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) (AA 32-126) protein (GST tag)
KIR2DL4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4) (AA 24-242) protein (hIgG-His-tag)KIR2DL4 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- KIR2DL4/CD158d (KIR2DL4) (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4))
- Alternative Name
- KIR2DL4/CD158D (KIR2DL4 Products)
- Synonyms
- G9P Protein, CD158D Protein, KIR103 Protein, KIR103AS Protein, KIR2DL4 Protein, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 Protein, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 Protein, KIR2DL4 Protein
- Background
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Background: KIR2DL4, also known as CD158d, is a member of the killer cell Ig-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.
Synonym: Killer Cell Immunoglobulin-Like Receptor 2DL4, CD158 Antigen-Like Family Member D, G9P, Killer Cell Inhibitory Receptor 103AS, KIR-103AS, MHC Class I NK Cell Receptor KIR103AS, CD158d, KIR2DL4, CD158D, KIR103AS
- Molecular Weight
- 25.1 kDa
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